Had the same issue after updating to 5.1.11.0G. Reinstalling the older versions of firmware haven't helped at all. (MEssage about old version). Eventually i Had to root the phone and go to build.prop and change ro.sf.hwrotation=180 to 0. When booting MEIZU is upside down, everuthing else is OK.

Question to flyme developers: How it is even possible that your update can do such harm to the phone? What your hands should do to make the screen flip upside down and still make the touchscreen work as always? (it was after OTA update)
Bravo Meizu!

You perform root procedure on your phone, then download any program like buildprop editor. Find build.prop file in system and change the value. To make it easier to manipulate with the phone using OTG mouse. Hope this helps.